Sanitizing Your Sponges Sponges are a great tool for cleaning they have a rough side to clean hard to clean areas plus pots and pans but they also have a soft side for those areas in your home that need a gentle cleaning. Sponges are great but can harbor millions of germs since we use them to clean so much. You can through that sponge away and buy a new one or you can sanitize it and reuse it. You can do this two ways. The first way is the easiest by putting the sponge in with the towels you bleach. If you don’t want to wait to do laundry you can simply put the sponge in the microwave for two minutes and it will kill 99% of the germs.